兔抗BAX(Ab-167)多克隆抗體

Background:

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c.

Applications:

WB, IF

Name of antibody:

BAX(Ab-167)

Immunogen:

Synthesized non-phosphopeptide derived from human Bax around the phosphorylation site of threonine 167 (F-G-T(p)-P-T).

Full name:

BCL2-associated X protein

Synonyms：

BCL2L4

SwissProt:

Q07812

WB Predicted band size:

21 kDa

WB Positive control:

HepG2 cells lysate

WB Recommended dilution:

500-3000

IF positive control:

LOVO cells

IF Recommend dilution:

100-500