購(gòu)物車
幫助
021-54845833/15800441009
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Background: |
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed:10636859, PubMed:15153520). |
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Applications: |
ELISA, IHC |
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Name of antibody: |
C5AR1 |
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Immunogen: |
Fusion protein of human C5AR1 |
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Full name: |
complement component 5a receptor 1 |
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Synonyms: |
C5A; C5AR; C5R1; CD88 |
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SwissProt: |
P21730 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human liver cancer and human esophagus cancer |
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IHC Recommend dilution: |
40-200 |
