兔抗CA4多克隆抗體

Background:

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This gene encodes a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and proximal renal tubules. Its exact function is not known; however, it may have a role in inherited renal abnormalities of bicarbonate transport.

Applications:

ELISA, WB, IHC

Name of antibody:

CA4

Immunogen:

Fusion protein of human CA4

Full name:

carbonic anhydrase IV

Synonyms：

CAIV; Car4; RP17

SwissProt:

P22748

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human colon cancer and human prostate cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

35 kDa

WB Positive control:

Human normal lung tissue

WB Recommended dilution:

500-2000