兔抗CARM1(Phospho-Ser228)多克隆抗體

Background:

This gene belongs to the protein arginine methyltransferase (PRMT) family. The encoded enzyme catalyzes the methylation of guanidino nitrogens of arginyl residues of proteins. The enzyme acts specifically on histones and other chromatin-associated proteins and is involved in regulation of gene expression. The enzyme may act in association with other proteins or within multi-protein complexes and may play a role in cell type-specific functions and cell lineage specification. A related pseudogene is located on chromosome 9.

Applications:

WB, IF

Name of antibody:

CARM1(Phospho-Ser228)

Immunogen:

Peptide sequence around phosphorylation site of serine 228(V-K-S(p)-N-N) derived from Human CARM1.

Full name:

coactivator-associated arginine methyltransferase 1

Synonyms：

PRMT4

SwissProt:

A6NN38

WB Predicted band size:

66 kDa

WB Positive control:

A431 cells lysates untreated or treated with EGF (200ng/ml 5min)

WB Recommended dilution:

500-1000

IF positive control:

Hela cells

IF Recommend dilution:

100-200