兔抗CBX8多克隆抗體

Background:

Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

Applications:

ELISA, WB, IHC

Name of antibody:

CBX8

Immunogen:

Fusion protein of human CBX8

Full name:

chromobox 8

Synonyms:

PC3; RC1

SwissProt:

Q9HC52

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

50-100

WB Predicted band size:

43 kDa

WB Positive control:

231 and 293T cell lysates

WB Recommended dilution:

500-2000