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  • 兔抗CCM2多克隆抗體

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    • 品牌 : 通蔚生物
    • 目錄號 : TW4660
    • 應(yīng)用 : 僅用于科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
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中文名稱:兔抗CCM2多克隆抗體

英文名稱:
Anti-CCM2 rabbit polyclonal antibody

別      名:
CCM2 scaffolding protein; OSM; C7orf22; PP10187

相關(guān)類別: 一抗

儲      存: 冷凍(-20℃)

宿      主: Rabbit

抗      原: CCM2

反應(yīng)種屬: Human

標 記 物:
Unconjugate

克隆類型:
rabbit polyclonal

技術(shù)規(guī)格

Background:

This gene encodes a scaffold protein that functions in the stress-activated p38 Mitogen-activated protein kinase (MAPK) signaling cascade. The protein interacts with SMAD specific E3 ubiquitin protein ligase 1 (also known as SMURF1) via a phosphotyrosine binding domain to promote RhoA degradation. The protein is required for normal cytoskeletal structure, cell-cell interactions, and lumen formation in endothelial cells. Mutations in this gene result in cerebral cavernous malformations. Multiple transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, IHC

Name of antibody:

CCM2

Immunogen:

Fusion protein of human CCM2

Full name:

CCM2 scaffolding protein

Synonyms:

OSM; C7orf22; PP10187

SwissProt:

Q9BSQ5

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human esophagus cancer

IHC Recommend dilution:

20-100