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中文名稱： SHPK 抗原（重組蛋白）
英文名稱： SHPK Antigen (Recombinant Protein)
別 名： sedoheptulokinase; SHK; CARKL
儲 存： 冷凍（-20℃）
相關(guān)類別：抗原
技術(shù)規(guī)格
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Full name: |
sedoheptulokinase |
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Synonyms: |
SHK; CARKL |
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Swissprot: |
Q9UHJ6 |
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Gene Accession: |
BC020543 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. Sequence variation between this novel gene and known carbohydrate kinases suggests the possibility of a different substrate, cofactor or changes in kinetic properties distinguishing it from other carbohydrate kinases. The gene resides in a region commonly deleted in cystinosis patients, suggesting a role as a modifier for the cystinosis phenotype. The genomic region is also rich in Alu repetitive sequences, frequently involved in chromosomal rearrangements. |
