兔抗XRN1多克隆抗體

Background:

This gene encodes a member of the 5'-3' exonuclease family. The encoded protein may be involved in replication-dependent histone mRNA degradation, and interacts directly with the enhancer of mRNA-decapping protein 4. In addition to mRNA metabolism, a similar protein in yeast has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly. Mutations in this gene are associated with osteosarcoma, suggesting that the encoded protein may also play a role in bone formation. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, WB, IHC

Name of antibody:

XRN1

Immunogen:

Synthetic peptide of human XRN1

Full name:

5'-3' exoribonuclease 1

Synonyms:

SEP1

SwissProt:

Q8IZH2

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer and human lung cancer

IHC Recommend dilution:

10-50

WB Predicted band size:

194 kDa

WB Positive control:

Hela，231 and K562 cell lysates

WB Recommended dilution:

500-2000