兔抗CDC23多克隆抗體

Background:

The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.

Applications:

ELISA, WB

Name of antibody:

CDC23

Immunogen:

Fusion protein of human CDC23

Full name:

cell division cycle 23

Synonyms:

APC8; CUT23; ANAPC8

SwissProt:

Q9UJX2

ELISA Recommended dilution:

5000-10000

WB Predicted band size:

69 kDa

WB Positive control:

HEPG2, Hela, Jurkat cell lysates

WB Recommended dilution:

200-1000