兔抗CDC25A(Phospho-Ser124)多克隆抗體

Background:

CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated.

Applications:

WB

Name of antibody:

CDC25A(Phospho-Ser124)

Immunogen:

Peptide sequence around phosphorylation site of Serine 124 (S-H-S(p)-D-S) derived from Human CDC25A.

Full name:

cell division cycle 25A

Synonyms：

CDC25A2

SwissProt:

P30304

WB Predicted band size:

59 kDa

WB Positive control:

293 cells lysates with UV

WB Recommended dilution:

500-1000