兔抗ZFP36多克隆抗體

Background:

mRNA-binding protein involved in post-transcriptional regulation of AU-rich element (ARE)-containing mRNAs. Acts by specifically binding ARE-containing mRNAs and promoting their degradation. Recruits deadenylase CNOT7 (and probably the CCR4-NOT complex) via association with CNOT1. Plays a key role in the post-transcriptional regulation of tumor necrosis factor (TNF). Plays a key role in the post-transcriptional regulation of tumor necrosis factor (TNF).

Applications:

ELISA, IHC

Name of antibody:

ZFP36

Immunogen:

Fusion protein of human ZFP36

Full name:

ZFP36 ring finger protein

Synonyms:

TTP; G0S24; GOS24; TIS11; NUP475; zfp-36; RNF162A

SwissProt:

P26651

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human brain and human gastric cancer

IHC Recommend dilution:

40-200