兔抗ZGPAT多克隆抗體

Background:

Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis.

Applications:

ELISA, IHC

Name of antibody:

ZGPAT

Immunogen:

Fusion protein of human ZGPAT

Full name:

zinc finger CCCH-type and G-patch domain containing

Synonyms:

ZIP; ZC3H9; GPATC6; GPATCH6; ZC3HDC9; KIAA1847

SwissProt:

Q8N5A5

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human thyroid cancer

IHC Recommend dilution:

40-200