兔抗CDK2(Phospho-Thr160)多克隆抗體

Background:

This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity of this protein is especially critical during the G1 to S phase transition. This protein associates with and regulated by other subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A), and p27Kip1 (CDKN1B)

Applications:

WB, IHC

Name of antibody:

CDK2(Phospho-Thr160)

Immunogen:

Peptide sequence around phosphorylation site of threonine 160 (T-Y-T(p)-H-E) derived from Human CDK2

Full name:

cyclin-dependent kinase 2

Synonyms:

CDKN2; p33(CDK2)

SwissProt:

P24941

IHC positive control:

Human breast carcinoma

IHC Recommend dilution:

50-100

WB Predicted band size:

34 kDa

WB Positive control:

Hela cells treated with UV

WB Recommended dilution:

500-1000