兔抗CERK多克隆抗體

Background:

CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis, and inflammation. Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. Binds phosphoinositides.

Applications:

ELISA, IHC

Name of antibody:

CERK

Immunogen:

Fusion protein of human CERK

Full name:

ceramide kinase

Synonyms：

LK4; hCERK; dA59H18.2; dA59H18.3

SwissProt:

Q8TCT0

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human tonsil and Human thyroid cancer

IHC Recommend dilution:

25-100