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  • USP14 抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號 : TW6341
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存:20
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中文名稱: USP14 抗原(重組蛋白)

英文名稱 USP14 Antigen (Recombinant Protein)

別    名: ubiquitin specific peptidase 14; TGT

相關(guān)類別:抗原

儲    存: 冷凍(-20℃)

概     述

Fusion protein corresponding to a region derived from 295-494 amino acids of human USP14



技術(shù)規(guī)格

Full name:

ubiquitin specific peptidase 14

Synonyms:

TGT

Swissprot:

P54578

Gene Accession:

BC003556

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.