小鼠抗AURKA單克隆抗體

Background:

The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.

Applications:

WB, IF

Name of antibody:

AURKA

Immunogen:

Fusion protein of human AURKA

Full name:

aurora kinase A

Synonyms:

AIK; ARK1; AURA; BTAK; STK6; STK7; STK15; PPP1R47

SwissProt:

O14965

WB Predicted band size:

46 kDa

WB Positive control:

COS7 and SW480 cell lysates

WB Recommended dilution:

500-2000

IF positive control:

Hela cells

IF Recommend dilution:

50-100