小鼠抗COL6A1單克隆抗體

Background:

The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy.

Applications:

WB

Name of antibody:

COL6A1

Immunogen:

Fusion protein of human COL6A1

Full name:

collagen type VI alpha 1 chain

Synonyms:

OPLL; BTHLM1; UCHMD1

SwissProt:

P12109

WB Predicted band size:

109 KD

WB Positive control:

293T cell lysate

WB Recommended dilution:

200-1000