購物車
幫助
021-54845833/15800441009
英文名稱： ZYX Antigen (Recombinant Protein)
別 名： zyxin; ESP-2; HED-2
相關類別：抗原
儲 存： 冷凍（-20℃）
概 述
|
Full name: |
zyxin |
|
Synonyms: |
ESP-2; HED-2 |
|
Swissprot: |
Q15942 |
|
Gene Accession: |
BC008743 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. |
