小鼠抗ERCC3單克隆抗體

Background:

This gene encodes an ATP-dependent DNA helicase that functions in nucleotide excision repair. The encoded protein is a subunit of basal transcription factor 2 (TFIIH) and, therefore, also functions in class II transcription. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy. Alternative splicing results in multiple transcript variants.

Applications:

WB, IHC

Name of antibody:

ERCC3

Immunogen:

Fusion protein of human ERCC3

Full name:

ERCC excision repair 3, TFIIH core complex helicase subunit

Synonyms:

XPB; BTF2; TTD2; GTF2H; RAD25; TFIIH

SwissProt:

P19447

IHC positive control:

Human colon tissue and Human colorectal cancer; Human lung tissue and Human prostate tissue

IHC Recommend dilution:

500-1000

WB Predicted band size:

89 KD

WB Positive control:

Hela, Jurkat, 293T lysates

WB Recommended dilution:

200-1000