小鼠抗EZR單克隆抗體

Background:

The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.

Applications:

WB

Name of antibody:

EZR

Immunogen:

Fusion protein of human EZR

Full name:

ezrin

Synonyms:

CVL; CVIL; VIL2; HEL-S-105

SwissProt:

P15311

WB Predicted band size:

69 kDa

WB Positive control:

MCF7, 3T3 and A549 cell, Rat brain tissue lysates

WB Recommended dilution:

1000-5000