兔抗HEY2多克隆抗體

Background:

This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The encoded protein forms homo- or hetero-dimers that localize to the nucleus and interact with a histone deacetylase complex to repress transcription. Expression of this gene is induced by the Notch signal transduction pathway. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternatively spliced transcript variants have been found, but their biological validity has not been determined.

Applications:

WB

Name of antibody:

HEY2

Immunogen:

Synthesized peptide derived from internal of human HEY2.

Full name:

hes-related family bHLH transcription factor with YRPW motif 2

Synonyms：

GRL; CHF1; HRT2; HERP1; HESR2; bHLHb32; GRIDLOCK

SwissProt:

Q9UBP5

WB Predicted band size:

36 kDa

WB Positive control:

K562 cells lysate

WB Recommended dilution:

500-3000