兔抗HOXA5多克隆抗體

Background:

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis.

Applications:

ELISA, IHC

Name of antibody:

HOXA5

Immunogen:

Synthetic peptide of human HOXA5

Full name:

homeobox A5

Synonyms：

HOX1; HOX1C; HOX1.3

SwissProt:

P20719

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer and human esophagus cancer

IHC Recommend dilution:

10-50