購(gòu)物車
幫助
021-54845833/15800441009
抗 原： IDH3B
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
|
Background: |
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
|
Applications: |
ELISA, WB, IHC |
|
Name of antibody: |
IDH3B |
|
Immunogen: |
Fusion protein of human IDH3B |
|
Full name: |
isocitrate dehydrogenase 3 (NAD+) beta |
|
Synonyms： |
RP46; H-IDHB |
|
SwissProt: |
O43837 |
|
ELISA Recommended dilution: |
1000-2000 |
|
IHC positive control: |
Human thyroid cancer |
|
IHC Recommend dilution: |
25-100 |
|
WB Predicted band size: |
42 kDa |
|
WB Positive control: |
HepG2 cells and mouse kidney tissue, lovo cells and mouse eyes tissue, hela cells |
|
WB Recommended dilution: |
200-1000 |
