兔抗ITGAX多克隆抗體

Background:

This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles.

Applications:

ELISA, IHC

Name of antibody:

ITGAX

Immunogen:

Synthetic peptide of human ITGAX

Full name:

integrin, alpha X (complement component 3 receptor 4 subunit)

Synonyms:

CD11C, SLEB6

SwissProt:

P20702

IHC positive control:

Human gastric cancer

IHC Recommend dilution:

15-50