購(gòu)物車(chē)
幫助
021-54845833/15800441009
技術(shù)規(guī)格
|
Background: |
This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms. |
|
Applications: |
WB, IF, IP |
|
Name of antibody: |
SIRT6 |
|
Immunogen: |
Fusion protein of human SIRT6 |
|
Full name: |
sirtuin 6 |
|
Synonyms: |
SIR2L6 |
|
SwissProt: |
Q8N6T7 |
|
WB Predicted band size: |
39 kDa |
|
WB Positive control: |
Jurkat, MCF7, HCT116, K562, COS7, C2C12, 3T3 and Hela cell lysates |
|
WB Recommended dilution: |
500-2000 |
|
IF positive control: |
Hela cells |
