購(gòu)物車(chē)
幫助
021-54845833/15800441009
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Background: |
Metallocarboxypeptidase that may play a role in the processing of tubulin. Knockdown of AGBL2 results in a failure of the cell to detyrosinate the C-terminal EEY region of α-tubulin and indicates that, it is a candidate for the long sought after tubulin tyrosine carboxypeptidase important in regulation of microtubule dynamics. RARRES1, its interacting partners AGBL2, Eg5/KIF11, another EEY bearing protein (EB1), and the microtubule tyrosination cycle are important in tumorigenesis and identify a novel area for therapeutic intervention. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
AGBL2 |
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Immunogen: |
Fusion protein of human AGBL2 |
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Full name: |
ATP/GTP binding protein-like 2 |
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SwissProt: |
Q5U5Z8 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human thyroid cancer and human lung cancer |
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IHC Recommend dilution: |
25-100 |
