兔抗CIAO2A多克隆抗體

Background:

Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (PubMed:23891004). As a CIA complex component and in collaboration with CIAO1 specifically matures ACO1 and stabilizes IREB2, connecting cytosolic iron-sulfur protein maturation with cellular iron regulation (PubMed:23891004). May play a role in chromosome segregation through establishment of sister chromatid cohesion. May induce apoptosis in collaboration with APAF1 (PubMed:25716227).

Applications:

ELISA, WB

Name of antibody:

CIAO2A

Immunogen:

Fusion protein of human CIAO2A

Full name:

cytosolic iron-sulfur assembly component 2A

Synonyms:

CIA2A; FAM96A

SwissProt:

Q9H5X1

WB Predicted band size:

18 kDa

WB Positive control:

Human fetal intestines tissue

WB Recommended dilution:

200-1000