兔抗CLSTN1多克隆抗體

Background:

This gene is a member of the calsyntenin family, a subset of the cadherin superfamily. The encoded transmembrane protein, also known as alcadein-alpha, is thought to bind to kinesin-1 motors to mediate the axonal anterograde transport of certain types of vesicle. Amyloid precursor protein (APP) is trafficked via these vesicles and so this protein is being investigated to see how it might contribute to the mechanisms underlying Alzheimer's disease. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, IHC

Name of antibody:

CLSTN1

Immunogen:

Synthetic peptide of human CLSTN1

Full name:

calsyntenin 1

Synonyms:

CST-1; CSTN1; CDHR12; PIK3CD; ALC-ALPHA; XB31alpha; alcalpha1; alcalpha2

SwissProt:

O94985

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer and human ovarian cancer

IHC Recommend dilution:

10-50