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  • MITF抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號 : TW16845
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存:40
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中文名稱: MITF抗原(重組蛋白)

文名稱: MITF Antigen (Recombinant Protein)

別      名: MI; WS2; CMM8; WS2A; COMMAD; bHLHe32

儲      存: 冷凍(-20℃)

相關(guān)類別: 抗原

概述

Fusion protein corresponding to a region derived from 354-526 amino acids of human MITF

技術(shù)規(guī)格

Full name:

melanogenesis associated transcription factor

Synonyms:

MI; WS2; CMM8; WS2A; COMMAD; bHLHe32

Swissprot:

O75030

Gene Accession:

BC026961

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.