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  • PLAUR抗原（重組蛋白）

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    • 品牌 : 通蔚生物
    • 目錄號 : TW17052
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存：40
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中文名稱： PLAUR抗原（重組蛋白）

英文名稱： PLAUR Antigen (Recombinant Protein)

別      名： CD87; UPAR; URKR; U-PAR

儲(chǔ)      存： 冷凍（-20℃）

相關(guān)類別： 抗原

概述

Fusion protein corresponding to a region derived from 23-305 amino acids of human PLAUR

技術(shù)規(guī)格

Full name:

Plasminogen activator, urokinase receptor

Synonyms:

CD87; UPAR; URKR; U-PAR

Swissprot:

Q03405

Gene Accession:

BC002788

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.