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  • PTHLH抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號 : TW17126
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存:40
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中文名稱: PTHLH抗原(重組蛋白)

英文名稱: PTHLH Antigen (Recombinant Protein)

別       名: HHM, PLP, BDE2, PTHR, PTHRP

儲       存: 冷凍(-20℃)

相關(guān)類別: 抗原

概述

Fusion protein corresponding to a region derived from 37-177 amino acids of human PTHLH

技術(shù)規(guī)格

Full name:

parathyroid hormone-like hormone

Synonyms:

HHM, PLP, BDE2, PTHR, PTHRP

Swissprot:

P12272

Gene Accession:

BC005961

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a member of the parathyroid hormone family. This hormone regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. This hormone is involved in lactation possibly by regulating the mobilization and transfer of calcium to the milk. The receptor of this hormone, PTHR1, is responsible for most cases of humoral hypercalcemia of malignancy. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, in-frame and downstream of the initiator AUG codon, to give rise to nuclear forms of this hormone.