中文名稱: FTO抗原(重組蛋白)
英文名稱: FTO Antigen (Recombinant Protein)
別 名: ALKBH9
儲 存: 冷凍(-20℃)
相關(guān)類別: 抗原
概 述:
Fusion protein corresponding to a region derived from 456-505 amino acids of human FTO |
Full name: |
fat mass and obesity associated |
Synonyms: |
ALKBH9 |
Swissprot: |
Q9C0B1 |
Gene Accession: |
BC003583 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. |