中文名稱: ZNF496 抗原(重組蛋白)
英文名稱: ZNF496 Antigen (Recombinant Protein)
別 名: zinc finger protein 496; NIZP1; ZFP496; ZSCAN49; ZKSCAN17
相關(guān)類別:抗原
儲 存: 冷凍(-20℃)
概 述
Full name: |
zinc finger protein 496 |
Synonyms: |
NIZP1; ZFP496; ZSCAN49; ZKSCAN17 |
Swissprot: |
Q96IT1 |
Gene Accession: |
BC007263 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF496 (Zinc finger protein 496), also known as ZKSCAN17 or NIZP1, is a 587 amino acid member of the Krüppel C2H2-type zinc-finger protein family and is thought to act as a transcriptional repressor. Localized to the nucleus, ZNF496 contains one SCAN box domain, one KRAB domain and five C2H2-type zinc fingers through which it may convey DNA, RNA and protein binding capabilities. |