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  • PIM1抗原（重組蛋白）

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    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW17547
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫(kù)存：90
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中文名稱：PIM1抗原（重組蛋白）

英文名稱： PIM1 Antigen (Recombinant Protein)

別      名： PIM

儲(chǔ)      存： 冷凍（-20℃）

相關(guān)類別： 抗原

概  述：

Fusion protein corresponding to C terminal 228 amino acids of human PIM1


技術(shù)規(guī)格：

Full name:

pim-1 oncogene

Synonyms:

PIM

Swissprot:

P11309

Gene Accession:

BC020224

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons.