購物車
幫助
021-54845833/15800441009
中文名稱：TLR5抗原（重組蛋白）
英文名稱： TLR5 Antigen (Recombinant Protein)
別 名： TIL3; SLEB1
儲 存： 冷凍（-20℃）
相關(guān)類別： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 3-180 amino acids of human TLR5 |
|
Full name: |
toll-like receptor 5 |
|
Synonyms: |
TIL3; SLEB1 |
|
Swissprot: |
O60602 |
|
Gene Accession: |
BC109119 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease. |
