歡迎來到上海通蔚!

021-54845833/15800441009

品質(zhì)保證 · 通蔚試劑

當(dāng)前位置: 首頁 > 科研產(chǎn)品 > 科研抗體 > 其他抗體 > PDZD3抗原(重組蛋白)

產(chǎn)品中心

  • PDZD3抗原(重組蛋白)

    規(guī)格:
    數(shù)量:

    購買數(shù)量

    價(jià)格:
    • 品牌 : 通蔚生物
    • 目錄號(hào) : TW18042
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存:40
  • 商品詳情
  • 參考文獻(xiàn)
  • 說明書下載
  • 商品評(píng)論0
  • 相關(guān)產(chǎn)品

中文名稱:PDZD3抗原(重組蛋白)

英文名稱: PDZD3 Antigen (Recombinant Protein)

別      名: PDZ domain containing 3; IKEPP; PDZK2; NHERF4

儲(chǔ)      存: 冷凍(-20℃)

相關(guān)類別: 抗原

概述

Fusion protein corresponding to a region derived from 372-571 amino acids of human PDZD3

技術(shù)規(guī)格

Full name:

PDZ domain containing 3

Synonyms:

IKEPP; PDZK2; NHERF4

Swissprot:

Q86UT5

Gene Accession:

BC029042

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Guanylyl cyclase C (GCC, or GUCY2C; MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR; MIM 602421), followed by a net efflux of ions and water into the intestinal lumen. IKEPP is a regulatory protein that associates with GCC and regulates the amount of cGMP produced following receptor stimulation (Scott et al., 2002 [PubMed 11950846]).