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  • 兔抗MDC1(Phospho-Ser513)多克隆抗體

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    • 品牌 : 通蔚生物
    • 目錄號 : TW18204
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中文名稱:  兔抗MDC1(Phospho-Ser513) 多克隆抗體


英文名稱:  Anti-MDC1(Phospho-Ser513) rabbit polyclonal antibody


別      名:  NFBD1


相關(guān)類別:  一抗


儲      存:  冷凍(-20℃) 避光


宿      主:  Rabbit


抗      原:  MDC1(Phospho-Ser513)


反應(yīng)種屬:  Human


標(biāo)  記 物:  Unconjugate


克隆類型:  Unconjugate


技術(shù)規(guī)格

Background:

The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci. [provided by RefSeq, Jul 2008]

Applications:

IHC

Name of antibody:

MDC1(Phospho-Ser513)

Immunogen:

Peptide sequence around phosphorylation site of Serine 513(E-R-S(p)-Q-A) derived from Human MDC1.

Full name:

mediator of DNA-damage checkpoint 1

Synonyms:

NFBD1

SwissProt:

Q14676

IHC positive control:

Human brain tissue

IHC Recommend dilution:

50-100