中文名稱: 兔抗MDC1多克隆抗體
英文名稱: Anti-MDC1 rabbit polyclonal antibody
別 名: NFBD1
相關(guān)類別: 一抗
儲 存: 冷凍(-20℃)
宿 主: Rabbit
抗 原: MDC1
反應(yīng)種屬: Human
標(biāo) 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci. |
Applications: |
ELISA, IHC |
Name of antibody: |
MDC1 |
Immunogen: |
Synthetic peptide of human MDC1 |
Full name: |
Mediator of DNA-damage checkpoint 1 |
Synonyms: |
NFBD1 |
SwissProt: |
Q14676 |
ELISA Recommended dilution: |
2000-10000 |
IHC positive control: |
Human brain |
IHC Recommend dilution: |
100-300 |