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  • 兔抗MDC1多克隆抗體

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    • 品牌 : 通蔚生物
    • 目錄號 : TW18206
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
    • 商品庫存:80
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中文名稱:  兔抗MDC1多克隆抗體


英文名稱:  Anti-MDC1 rabbit polyclonal antibody


別       名:  NFBD1


相關(guān)類別:  一抗


儲      存:  冷凍(-20℃)


宿      主:  Rabbit


抗      原:  MDC1


反應(yīng)種屬:  Human


標(biāo)  記 物:  Unconjugate


克隆類型:  rabbit polyclonal


技術(shù)規(guī)格

Background:

The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci.

Applications:

ELISA, IHC

Name of antibody:

MDC1

Immunogen:

Synthetic peptide of human MDC1

Full name:

Mediator of DNA-damage checkpoint 1

Synonyms:

NFBD1

SwissProt:

Q14676

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human brain

IHC Recommend dilution:

100-300