兔抗DLEC1多克隆抗體

Background:

The cytogenetic location of this gene is 3p21.3, and it is located in a region that is commonly deleted in a variety of malignancies. Down-regulation of this gene has been observed in several human cancers including lung, esophageal, renal tumors, and head and neck squamous cell carcinoma. In some cases, reduced expression of this gene in tumor cells is a result of aberrant promoter methylation. Several alternatively spliced transcripts have been observed that contain disrupted coding regions and likely encode nonfunctional proteins.

Applications:

ELISA, IHC

Name of antibody:

DLEC1

Immunogen:

Synthetic peptide corresponding to a region derived from 1727-1743 amino acids of human DLEC1

Full name:

deleted in lung and esophageal cancer 1

Synonyms:

F56; DLC1; DLC-1; CFAP81

SwissProt:

Q9Y238

ELISA Recommended dilution:

5000-10000

IHC Positive control:

Human esophagus cancer;Human colorectal cancer

IHC Recommended dilution:

10-50