兔抗DOK1 (phospho-Tyr398)多克隆抗體

Background:

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.

Applications:

WB, IHC

Name of antibody:

DOK1 (phospho-Tyr398)

Immunogen:

Synthetic peptide of human DOK1 (phospho-Tyr398)

Full name:

docking protein 1, 62kDa (downstream of tyrosine kinase 1) (phospho-Tyr398)

Synonyms：

P62DOK

SwissProt:

Q99704

IHC positive control:

Human breast carcinoma

IHC Recommend dilution:

50-100

WB Predicted band size:

62 kDa

WB Positive control:

K562 cells treated with H2O2

WB Recommended dilution:

500-1000