兔抗ELAC2多克隆抗體

Background:

The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

ELAC2

Immunogen:

Fusion protein of human ELAC2

Full name:

elaC ribonuclease Z 2

Synonyms:

ELC2; HPC2; COXPD17

SwissProt:

Q9BQ52

IHC positive control:

Human gastric cancer and human liver cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

92 kDa

WB Positive control:

LoVo and Hela cells

WB Recommended dilution:

200-1000