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    • 品牌 : 通蔚生物
    • 目錄號 : TW2023
    • 應(yīng)用 : 僅限于科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
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中文名稱：  兔抗UBR7多克隆抗體
英文名稱： Anti-UBR7 rabbit polyclonal antibody
別       名： ubiquitin protein ligase E3 component n-recognin 7 (putative); C14orf130
相關(guān)類別： 一抗

抗       原： UBR7
儲      存： 冷凍（-20℃）
宿      主： Rabbit

反應(yīng)種屬： Human, Mouse
標  記  物： Unconjugate

克隆類型： rabbit polyclonal
技術(shù)規(guī)格

Background:

Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). Ubr7 (ubiquitin protein ligase E3 component n-recognin 7), also known as C14orf130 or N-recognin-7, is a 425 amino acid protein that contains one UBR-type zinc finger and one PHD zinc finger. Participating in protein modification events within the N-end rule pathway, Ubr7 functions as an E3 ubiquitin-protein ligase that recognizes and binds proteins that contain destabilizing N-terminal residues, thereby leading to their ubiquitination and subsequent degradation.

Applications:

ELISA, WB, IHC

Name of antibody:

UBR7

Immunogen:

Fusion protein of human UBR7

Full name:

ubiquitin protein ligase E3 component n-recognin 7 (putative)

Synonyms:

C14orf130

SwissProt:

Q8N806

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human colorectal cancer;Human liver cancer

IHC Recommend dilution:

30-150

WB Predicted band size:

48 kDa

WB Positive control:

Hela cell lysate

WB Recommended dilution:

200-1000