英文名稱(chēng): Anti-NCR2 rabbit polyclonal antibody
別 名: LY95; CD336; NKP44; NK-p44; dJ149M18.1
相關(guān)類(lèi)別: 一抗
儲(chǔ) 存: 冷凍(-20℃)
宿 主: Rabbit
抗 原: NCR2
反應(yīng)種屬: Human
標(biāo) 記 物: Unconjugate
克隆類(lèi)型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
Natural cytotoxicity triggering receptor 2 is a protein that in humans is encoded by the NCR2 gene. NCR2 has also been designated as CD336 (cluster of differentiation 336). NKp44 is a natural cytotoxicity receptor that is is expressed on IL-2-activated human NK cells and may contribute to the increased efficiency of NK cells to mediate tumor cell lysis. NKp44 is composed of one Ig-like extracellular domain, a transmembrane segment, and a cytoplasmic domain. Prolactin up-regulates and cortisol down-regulates the surface expression of NKp44 at the transcriptional level. A cellular ligand for NKp44 (NKp44L) is expressed during HIV-1 infection and is correlated with the progression of CD4+ T cell depletion and an increase of viral load. |
Applications: |
ELISA, IHC |
Name of antibody: |
NCR2 |
Immunogen: |
Synthetic peptide of human NCR2 |
Full name: |
natural cytotoxicity triggering receptor 2 |
Synonyms: |
LY95; CD336; NKP44; NK-p44; dJ149M18.1 |
SwissProt: |
O95944 |
ELISA Recommended dilution: |
1000-5000 |
IHC positive control: |
Human liver cancer and Human lung cancer |
IHC Recommend dilution: |
50-200 |