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中文名稱： 兔抗PFKFB3多克隆抗體
英文名稱： Anti-PFKFB3 rabbit polyclonal antibody
別 名： PFK2; IPFK2; iPFK-2
相關(guān)類別： 一抗
儲 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： PFKFB3
反應(yīng)種屬： Human, Rat
標 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
The protein encoded by this gene belongs to a family of bifunctional proteins that are involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate (F2,6BP), and a fructose-2,6-biphosphatase activity that catalyzes the degradation of F2,6BP. This protein is required for cell cycle progression and prevention of apoptosis. It functions as a regulator of cyclin-dependent kinase 1, linking glucose metabolism to cell proliferation and survival in tumor cells. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. |
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Applications: |
ELISA, WB |
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Name of antibody: |
PFKFB3 |
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Immunogen: |
Synthetic peptide of human PFKFB3 |
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Full name: |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
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Synonyms: |
PFK2; IPFK2; iPFK-2 |
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SwissProt: |
Q16875 |
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ELISA Recommended dilution: |
5000-10000 |
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WB Predicted band size: |
60 kDa |
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WB Positive control: |
293T,A549,A431,Hela and Jurkat cell lysates |
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WB Recommended dilution: |
500-2000 |
