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  • 兔抗PIK3R3多克隆抗體

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    • 品牌 : 通蔚生物
    • 目錄號 : TW21669
    • 應(yīng)用 : 僅供科研使用
    • 保存條件 : 低溫保存
    • 貨期 : 現(xiàn)貨
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中文名稱:  兔抗PIK3R3多克隆抗體


英文名稱:  Anti-PIK3R3 rabbit polyclonal antibody


別       名:  p55; p55-GAMMA


相關(guān)類別:  一抗


儲      存:  冷凍(-20℃)


宿      主:  Rabbit


抗      原:  PIK3R3


反應(yīng)種屬:  Human, Mouse, Rat


標(biāo)  記  物:  Unconjugate


克隆類型:  rabbit polyclonal


技術(shù)規(guī)格

Background:

Phosphatidylinositol 3-kinase is a lipid kinase that phosphorylates the inositol ring of phosphatidylinositol and related compounds at the 3’ position. PI 3-kinase p55 (PIK3R3) is comprised of a catalytic subunit and a regulatory subunit. The human p55 protein is composed of a rare amino terminal region followed by a proline-rich motif and two Src homology 2 (SH2) domains. PI 3-kinase p55 mRNAs are expressed in most human fetal and adult tissues; predominant expression is observed in the adult testis. Splice variant(s) of PI 3-kinase p55 have been identified; one of which has a deletion of 36 amino acids at the amino terminus and another which has an insertion of 59 amino acids at position 256 between the SH2 domains. Research suggests that PI 3-kinase p55 interacts with the IGFIR (Insulin-like growth factor-I receptor) and IR (Insulin receptor) and may be involved in PI 3-kinase activation by these receptors.

Applications:

ELISA, WB, IHC

Name of antibody:

PIK3R3

Immunogen:

Synthetic peptide of human PIK3R3

Full name:

phosphoinositide-3-kinase, regulatory subunit 3 (gamma)

Synonyms:

p55; p55-GAMMA

SwissProt:

Q92569

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human lung cancer and Human gastric cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

54 kDa

WB Positive control:

Mouse brain, human fetal brain and mouse testis tissue, hela cells and human fetal kidney tissue

WB Recommended dilution:

500-2000