購(gòu)物車
幫助
021-54845833/15800441009
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Background: |
Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
SNAP25 |
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Immunogen: |
Fusion protein of human SNAP25 |
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Full name: |
Synaptosomal-associated protein, 25kDa |
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Synonyms： |
RIC4; SEC9; SNAP; RIC-4; SNAP-25; bA416N4.2; dJ1068F16.2 |
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SwissProt: |
P60880 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human brain and human thyroid cancer |
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IHC Recommend dilution: |
25-100 |
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WB Predicted band size: |
23 kDa |
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WB Positive control: |
Hela cells |
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WB Recommended dilution: |
500-2000 |
