購物車
幫助
021-54845833/15800441009
中文名稱： 兔抗ABCA4多克隆抗體
英文名稱： Anti-ABCA4 rabbit polyclonal antibody
別 名： FFM; RMP; ABCR; RP19; STGD; ABC10; ARMD2; CORD3; STGD1
相關(guān)類別： 一抗
儲 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： ABCA4
反應(yīng)種屬： Human
技術(shù)規(guī)格
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Background: |
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease, a form of juvenile-onset macular degeneration. Mutations in this gene are also associated with retinitis pigmentosa-19, cone-rod dystrophy type 3, early-onset severe retinal dystrophy, fundus flavimaculatus, and macular degeneration age-related 2. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
ABCA4 |
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Immunogen: |
Synthetic peptide of human ABCA4 |
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Full name: |
ATP-binding cassette, sub-family A (ABC1), member 4 |
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Synonyms： |
FFM; RMP; ABCR; RP19; STGD; ABC10; ARMD2; CORD3; STGD1 |
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SwissProt: |
P78363 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human cervical cancer and Human thyroid cancer |
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IHC Recommend dilution: |
50-200 |
