兔抗STAT1多克隆抗體

Background:

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.

Applications:

ELISA, WB, IHC

Name of antibody:

STAT1

Immunogen:

Fusion protein of human STAT1

Full name:

Signal transducer and activator of transcription 1-alpha/beta

Synonyms：

ISGF-3, STAT91

SwissProt:

P42224

ELISA Recommended dilution:

500-2000

IHC positive control:

Human lung cancer

IHC Recommend dilution:

15-60

WB Predicted band size:

87 kDa

WB Positive control:

NIH/3T3 cells

WB Recommended dilution:

250-1000