兔抗ATG4D多克隆抗體

Background:

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene belongs to the autophagy-related protein 4 (Atg4) family of C54 endopeptidases. Members of this family encode proteins that play a role in the biogenesis of autophagosomes, which sequester the cytosol and organelles for degradation by lysosomes.

Applications:

ELISA, IHC

Name of antibody:

ATG4D

Immunogen:

Fusion protein of human ATG4D

Full name:

autophagy related 4D, cysteine peptidase

Synonyms：

APG4D; AUTL4; APG4-D

SwissProt:

Q86TL0

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human thyroid cancer and human liver cancer

IHC Recommend dilution:

50-200