兔抗XRCC1多克隆抗體

Background:

The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

Applications:

ELISA, IHC

Name of antibody:

XRCC1

Immunogen:

Synthetic peptide of human XRCC1

Full name:

X-ray repair cross complementing 1

Synonyms:

RCC; SCAR26

SwissProt:

P18887

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human tonsil and Human cervical cancer

IHC Recommend dilution:

25-50